Instrumental Analysis

CHEM*3440

Fall 2006 Offering


Lecturer: Dan Thomas

MACN 120/121/128 x53961

SCIE 1316 x52388

dfthomas@uoguelph.ca
Lab Coordinator: Julie De Merchant SCIE 3113A x54861 jde@uoguelph.ca
Lab Demonstrator: Christa Brosseau MACN 135  

Lectures: Mon, Wed, Fri 8:30 - 9:20 A.M. in MACK 233

Laboratory: Thurs. 2:30 - 5:20 P.M. in SCIE 3105, Thurs. 7:00 - 9:50 P.M., Fri. 2:30 - 5:20 P.M.

Note: Lecture is cancelled on Friday, September 29 as I will be away that day.


Evaluation

Textbook Assignments: 10%

Spreadsheet Assignments: 10%

Laboratory: 30%

Mid-Term Exam: 20% (Date of exam is Tuesday, October 24, 7:00 - 9:00 P.M. It is to be held in MACK 233.)

Final Exam: 30% (Date of exam is Saturday, December 9 from 11:30 A.M. to 1:30 P.M.) Exam location is Crop Science 116/117.


Textbook: "Principles of Instrumental Analysis", Skoog, Holler, and Nieman (Thomson Learning Inc.)

You will need regular access to this book as you will be asked to read numerous chapters and the homework assignments are from the problems in the text. The textbook and several other texts that would be sueful for study are on reserve in the library.


Lecture Topics

  1. Statistical Methods for Analytical Chemistry.
  2. Analog Electronics. Elementary Circuit Analysis. Signal Modification by Filters. Operational Amplifiers.
  3. Digital Electronics. Sampling. Alias. DAC. ADC.
  4. Spectrometry. Beer's Law. Spectrometers. Absorbance. Transmittance.
  5. UV/Visible Spectrometry. Light sources, detectors, spectrometers. Analytical experiments.
  6. Luminescence Spectrometry. Fluorescence and Phosphorescence.
  7. Infrared Spectrometry. Fourier Transform, FTIR. Light sources, detectors, spectrometers.
  8. Raman Spectrometry. Comparison with IR
  9. Mass Spectrometry. Molecular analytes. Sources, Mass Analyzers, and Detectors.
  10. X-ray Fluorescence Spectrometry. Sources, Spectrometers, Detectors.
  11. Thermal Methods. TGA, DTA, DSC.
  12. Radiochemical Methods. Neutron Activation.

Lecture Notes

The lecture notes can be downloaded from here. They are available in pdf format.

Section 1 Chemical Instrumentation
Section 2 Statistics for Analytical Methods
Section 3 Electronics
Section 4 Signal vs. Noise
Section 5 Operational Amplifiers
Section 6 Digital Electronics
Section 7 Spectrometry
Section 8 UV/Visible Spectrometry
  2003 Mid-Term Exam and Solutions
  2004 Mid-Term Exam and Solutions
  2005 Mid-Term Exam and Solutions
  2006 Mid-Term Exam and Solutions
Section 9 Photoluminescence
Section 10

Infrared Spectrometry

Section 11 Raman Spectrometry
Section 12 Mass Spectrometry
Section 13 X-ray Spectrometry
Section 14 Thermal Methods
Section 15 Radiochemical Methods
  2004 Final Exam and Solutions
  2005 Final Exam and Solutions

Readings and Assignments

Read Textbook Chapter
Hand in Worked Solutions
Questions (if you do not have access to textbook)
Solutions
Due Date
Chapter 1 & Chapter 2

2-1, 2-3, 2-7, 2-14, 2-15, 2-18, 2-19

Note error in question 2-18(c). Capacitance should be 0.033. Also, answers in back of book are wrong for many of the answers for this question.

Also, you will need to use some equations from the book. For equation 2-49, the numerator should the number 1, not the variable I.

Also, they messed up the phase calculations in the impedance in an RC circuit. To be done correctly, it should really be done with complex arithmetic. They throw out all that extra information and then put it back in incorrectly. The phase angle calculation (equations 2-43 and 2-45) should have a minus sign in front of the arctan function. This is because the reactance is a negative quantity.

#1
#1
Sept 22
Chapter 3 & Chapter 4 3-1, 3-3, 3-5, 3-10, 3-14, 3-18 (None from Chapter 4)
#2
#2
Sept. 29
Chapter 5 5-7, 5-8, 5-9, 5-12
#3
#3
Oct 6
Chapter 6 & Chapter 7 6-14, 6-15, 7-12, 7-14, 7-15, 7-19
#4
#4
Oct 13
Chapter 13 13-1 a,b,c, 13-2 d,e,f, 13-5, 13-7, 13-11, 13-14, 13-30
#5
#5
Oct 20
Chapter 14 14-1, 14-2, 14-6, 14-7
#6
#6
Oct 27
Chapter 15 15-3, 15-4, 15-6, 15-7, 15-9
#7
#7
Nov 3
Chapter 16 16-3, 16-4, 16-5, 16-8, 16-9, 16-10, 16-12

#8

IR Chart

#8
Nov 10
Chapter 17 & Chapter 18 17-2, 17-3, 17-6, 17-9, 18-3, 18-4, 18-5, 18-6
#9
#9
Nov 17
Chapter 11 & Chapter 20 20-2, 20-5, 20-7, 20-10, 20-12, 20-13, 20-15 (None from chapter 11)
#10
#10
Nov 23
Chapter 12 12-6, 12-9, 12-11, 12-12
#11

#11

Dec 1

Spreadsheet Problems

Assignment Topic
Due Date
Solution

Calibration Curve: O2 Sensor

2 October

Excel file

or

PDF file

Calibration Curve: more complex response not this year
#2

Internal Standard: Laquinimod by Mass Spec

20 November

Excel file

or

PDF file

Standard Addition: Ethanol in Baker's Yeast by Near-Infrared Spectrometry

27 November

Excel file

or

PDF file

Savitzky-Golay Filtering not this year
#5

 


For information regarding this page, contact Dan Thomas.