Chem*4570 Applied Biochemistry

Chem*4570 Applied Biochemistry Fall 2003

Department of Chemistry and Biochemistry Home Page
University of Guelph Home Page

Instructor:

Dr. R.A.B. Keates

Rm 338, MacN Chemistry Wing
keates@chembio.uoguelph.ca

Lectures:

Monday 2:30, Wednesday 2:30, Friday 2:30

Chemistry & Micro Building C&M 260.
schedule

Office Hours:

Designated hours: Monday & Wednesday 3:30-5:00, but available for quick consultation in office at other times.

Examinations:

On Monday October 20, the class agreed to move the midterm exam Monday October 27 1:30-3:30 pm, provisionally in C&M 260 (we may overflow into 261).

The final examination will include lecture material from the beginning of the semester, with a slight emphasis on the second half. Time and location to be announced.

Grading:

Midterm exam		35%
Assignment(s)		20%
Final examination		45%
		===
		100%

The assignment will consist of a take home exercise to be done at a set time in week 10 or 11 of the semester.
Assignment in pdf format,

Texts:

One of the following advanced undergraduate Biochemistry texts will be useful,

Stryer, Biochemistry, 4rd edition, Freeman, 1994

Nelson and Cox, Lehninger's Principles of Biochemistry, 3rd Ed 2001

Voet and Voet, Biochemistry 2nd Ed., Wiley, 1995.

Method of Presentation:

Three lectures per week.

Objectives:

A study of the production methods and applications of biochemistry.

Sample midterm exam F-99 Grading key for sample midterm exam F-99

Lecture schedule.		(subject to minor adjustment at instructor's discretion).
Lecture(s)		Topic
Lecture 1		Survey of products of industrial biochemistry
Lecture 2		Aerobic glycolysis and ethanol production in yeast
Lecture 3		Diversion of metabolism to glycerol in yeast
Lecture 4		Anaerobic pathways in other organisms: butyric acid, butanol and acetone
Lecture 5, Lecture 6		Glutamate and lysine production
Lecture 7, Lecture 8, Lecture 9, Lecture 10 Lecture 11, Lecture 12 Lecture 13		Promoting overproduction
Lecture 14, Lecture 15 Lecture 16, Lecture 17 Lecture 18		Antibiotics and their biosynthesis
Lecture 19		Enzyme technology
Lecture 20		Review class
Lecture 21		Enzyme technology
Lecture 22, Lecture 23 Lecture 24		Biotransformation, oxygenases and steroids
Lecture 25, Lecture 26		Analytical applications of enzymes
Lecture 27, Lecture 28		Antibody structure
Lecture 29, Lecture 30 Lecture 31, Lecture 32		Antibody production and applications
33		Review